维生素C通过向GAPDH选择性地杀死KRAS和BRAF突变结直肠癌细胞

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Jihye Yun1, Edouard Mullarky2, Changyuan Lu3

  • 1Meyer Cancer Center, Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

Science (New York, N.Y.)
|November 7, 2015
PubMed
概括

高剂量的维生素C通过诱导氧化应激和能量危机选择性地杀死具有KRAS或BRAF突变的结直肠癌细胞. 这一发现为这些难以治疗的癌症提供了潜在的新疗法.

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