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Updated: Mar 30, 2026

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

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通过CTLA-4阻断的抗癌免疫疗法依赖于肠道微生物群

Marie Vétizou1, Jonathan M Pitt1, Romain Daillère1

  • 1Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), 114 rue Edouard Vaillant, 94805 Villejuif, France. INSERM U1015, GRCC, Villejuif, France. University of Paris Sud XI, Kremlin-Bicêtre, France.

Science (New York, N.Y.)
|November 7, 2015
PubMed
概括

使用对CTLA-4 (细胞毒性T淋巴细胞相关蛋白4) 抗体的癌症免疫疗法依赖于特定的肠道细菌,特别是Bacteroides物种,以获得有效性.

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