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Updated: Mar 30, 2026

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Fezf2为免疫耐受性编排一个自抗原表达的胸膜程序

Hiroyuki Takaba1, Yasuyuki Morishita2, Yoshihiko Tomofuji3

  • 1Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan; Takayanagi Osteonetwork Project, Exploratory Research for Advanced Technology Program, Japan Science and Technology Agency (JST), Tokyo 113-0033, Japan.

Cell
|November 7, 2015
PubMed
概括

Fezf2 是一种新型的转录因子,可以独立于 Aire 调节胸腺内受组织限制的抗原 (TRA). 这一发现揭示了建立免疫耐受性和预防自身免疫的第二个关键途径.

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