咖啡消费与3个大前景群体的总和因果特定死亡率的关联
Ming Ding1, Ambika Satija1, Shilpa N Bhupathiraju1
1From Departments of Nutrition (M.D., A.S., S.N.B., Y.H., Q.S., W.W., R.M.v.D., F.B.H.) and Epidemiology (M.D., A.S., W.W., F.B.H.), Harvard School of Public Health, Boston, MA; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (Q.S., W.W., F.B.H.); Department of Epidemiology, Fairbanks School of Public Health (J.H.) and Melvin and Bren Simon Cancer Center (J.H.), Indiana University, Indianapolis; Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPAZ, CIBER of Epidemiology and Public Health, Madrid, Spain (E.L.-G.); and Saw Swee Hock School of Public Health and Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore (R.M.v.D.).
饮用咖啡因和无咖啡因咖啡因的风险较低. 适度饮用,每天最多5杯,对整体死亡率有最显著的好处.
科学领域:
- 流行病学
- 营养科学
- 公共卫生
背景情况:
- 咖啡消费与死亡风险之间的关系尚未完全理解.
- 之前的研究对咖啡因和无咖啡因咖啡的摄入有不确定的结果.
- 研究不同种类咖啡对死亡率的影响对于公共卫生指导至关重要.
研究的目的:
- 检查咖啡因和无咖啡因咖啡的消费与随后的死亡风险之间的关系.
- 分析与咖啡摄入有关的特定原因死亡率.
- 提供基于证据的关于咖啡消费对健康的影响的见解.
主要方法:
- 涉及护士健康研究 (NHS),NHS II和卫生专业人员后续研究的大型前性队列研究.
- 使用半量化食物频率调查问卷评估咖啡的消费.
- 在相当长的随访人年 (4,690,072人年) 中分析死亡率数据.
主要成果:
- 与非饮用者相比,咖啡消费 (每天1-5杯) 与死亡风险降低有关.
- 较高的摄入量 (每天超过5杯) 与死亡风险没有显著关联.
- 对于含咖啡因和不含咖啡因的咖啡,以及心血管疾病,神经疾病和自杀的死亡,反向关联是显著的.
结论:
- 咖啡因含量,咖啡因含量和咖啡因含量较高的咖啡因与总死亡风险较低有关.
- 咖啡消费对包括心血管和神经疾病在内的特定死因有保护作用.
- 研究结果表明,适度饮用咖啡可以成为健康生活方式的一部分.
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