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相关概念视频

Attention-Deficit/Hyperactivity Disorder01:30

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
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Autism Spectrum Disorder01:19

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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
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Intellectual Disability01:29

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Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
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The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such...
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Updated: Mar 30, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
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通过研究和干预措施减少神经发育障碍和残疾

Michael J Boivin1,2, Angelina M Kakooza3, Benjamin C Warf4

  • 1Department of Psychiatry, College of Osteopathic Medicine, 965 Fee Road, East Fee Hall Room 225, Michigan State University, East Lansing, Michigan 48824, USA.

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|November 19, 2015
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概括

了解神经发育障碍的遗传和表观遗传原因的进展对于开发有效的干预措施至关重要. 低收入和中等收入国家的战略性跨学科研究可以显著改善全球儿童健康和发展.

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科学领域:

  • 神经科学
  • 遗传学
  • 发育生物学
  • 公共卫生

背景情况:

  • 神经发育涉及整个生命中遗传,大脑,认知,情感和行为过程之间的复杂相互作用.
  • 由遗传和环境风险影响的神经发育的障碍会导致神经发育障碍和残疾.
  • 低收入和中等收入国家 (LMIC) 的研究对于全球解决这些疾病至关重要.

研究的目的:

  • 突出了解和改善神经发育障碍的进展,特别是在LMICs.
  • 确定预防,治疗和康复的战略研究机会.
  • 强调神经发育研究的跨学科融合的重要性.

主要方法:

  • 对神经发育障碍的LMIC研究创新进行审查并提供示例.
  • 整合基因型绘制与环境和文化因素.
  • 检查对神经发育风险和性的表观遗传影响.

主要成果:

  • 在LMIC中识别,监测和治疗神经发育障碍方面的创新.
  • 通过综合基因型绘制开发预防和康复干预措施.
  • 增强对表观遗传因素如何影响神经发育结果的理解.

结论:

  • 环境,大脑/行为和遗传学/表观遗传学之间的交叉研究是关键.
  • 综合性科学方法正在为神经发育障碍创造新技术和干预措施.
  • 这些努力支持儿童健康和发展作为人权的全球任务.