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Updated: May 5, 2026

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在聚合诱导自组合过程中将纳米粒子加载到块共聚物囊中:封装效率和热触发释放

Charlotte J Mable1, Rebecca R Gibson1, Sylvain Prevost2

  • 1Department of Chemistry, University of Sheffield , Brook Hill, Sheffield, South Yorkshire S3 7HF, United Kingdom.

Journal of the American Chemical Society
|November 25, 2015
PubMed
概括

聚合物囊泡有效地使用聚合诱导自组装 (PISA) 封装纳米粒子. 这些含有的囊泡提供受控释放, 作为生物医学应用的模型,

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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