关于贫血和早产的事实和文物
M A Klebanoff1, P H Shiono, H W Berendes
1Prevention Research Program, National Institute of Child Health and Human Development, Bethesda, MD 20892.
JAMA
|July 28, 1989
概括
怀孕期间的贫血与早产的联系很弱,特别是在第三个三个月的早期. 这项研究发现贫血并不是早产的主要原因.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 血液学 血液学 血液学
背景情况:
- 贫血是怀孕期间常见的疾病.
- 它在早产中的作用,特别是在多样化的人口中,需要进一步研究.
研究的目的:
- 为了前性地研究贫血和早产之间的联系.
- 调查贫血是否有助于在黑人妇女中观察到的高早产率.
主要方法:
- 这是一项针对35,423例怀孕的前性研究.
- 在贫血和非贫血妇女之间的早产发病率的比较,在妊娠的第三季度每周.
- 从怀孕25周到孕期血红素变化的分析,与婴儿出生体重和母亲的种族相关.
主要成果:
- 在第三季度早期的贫血和早产之间发现了一个微弱的关联.
- 怀孕早期的贫血并不能解释黑人妇女早产率的增加.
- 怀孕30周后的贫血与早产无关.
- 黑人和白人妇女分娩的血红素水平从25周增加到期.
- 贫血和早产之间的关联在28周时表现最强,随着临近产期而减少.
- 在早产和产后分娩的妇女之间比较血红素水平,产生了虚假的剂量反应效应.
结论:
- 贫血不是导致早产的重要因素.
- 方法问题,比如比较分娩妇女的血压,可能会导致结果偏差.
- 进一步的研究应该考虑这些偏见在评估贫血对怀孕结果的影响时.
相关概念视频
Blood Transfusion and Agglutination
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Disorders of Erythrocytes
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Rh Blood Group
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
Fetal Circulation
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Factors Affecting Erythropoiesis
The cardiovascular system regulates the number of erythrocytes in the bloodstream to ensure optimal oxygen transport. It also prevents over-proliferation of these cells, which helps to maintain blood viscosity and flow rate.
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...


