四柱性大动脉:特征,相关的结构性心血管异常和临床结果
Michael Y C Tsang1, Muaz M Abudiab1, Naser M Ammash1
1From Divisions of Cardiovascular Diseases (M.Y.C.T., N.M.A., V.T.N., P.A.P.) and Anatomic Pathology (W.D.E.), Mayo Clinic, Rochester, MN; and Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ (M.M.A., T.Z.N.).
Circulation
|December 5, 2015
概括
四柱动脉 (QAV) 是一种罕见的缺陷,发生在0. 006%的患者中. 有关条件如大动脉扩张和吐是常见的,但长期生存仍然很好.
科学领域:
- 心脏病学
- 遗传性心脏病
- 心声检查
背景情况:
- 四动脉 (QAV) 是一种罕见的先天性心脏缺陷.
- 了解它的流行,相关异常和长期结果至关重要.
研究的目的:
- 在大型心声数据库中确定QAV的频率.
- 在QAV患者中表征相关心血管异常.
- 描述诊断为QAV的个体的长期结果.
主要方法:
- 一个大型心声数据库的回顾性分析.
- 包括在1975年1月1日至2014年3月14日期间被诊断患有QAV的患者.
- 评估QAV类型,相关的心脏异常,以及患者随访数据.
主要成果:
- 在50名患者中诊断出QAV,代表0. 006%的频率.
- 大动脉扩张 (29%) 和中度至严重的大动脉吐 (26%) 是常见的发现.
- 其他心脏异常存在于32%的患者中,8名患者需要主动脉手术,主要是严重的吐.
结论:
- 大动脉扩张和其他心脏结构异常在QAV患者中相对常见.
- 大动脉反是主要的血液动力学问题和手术指示.
- QAV患者的长期存活率很好,在5年后为91. 5%,在10年后为87. 7%.
相关概念视频
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
874
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
874
Mitral Stenosis II: Clinical features and Diagnostic Tests
443
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
443
Aortic Regurgitation I: Introduction
1.2K
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.2K
Cardiovascular System Abnormal Findings II: Auscultation
773
Auscultation, an essential part of a heart examination, is done using a stethoscope. It provides crucial information about heart function and possible heart problems. Due to heart problems, abnormal sounds can be heard during systole or diastole. These sounds include S3 and S4 gallops, opening snaps, systolic clicks, and murmurs.
Abnormal Heart Sounds
Gallops:
Abnormal Heart Sounds
Gallops:
773
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
782
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
782
Heart Valves
13.7K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
13.7K


