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表皮IL-18平衡控制大肠炎中的屏障功能

Roni Nowarski1, Ruaidhrí Jackson1, Nicola Gagliani1

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Cell
|December 7, 2015
PubMed
概括

通过破坏肠道屏障来驱动性结肠炎. 阻断肠上皮细胞中的IL-18信号,可以防止结肠炎并保护杯状细胞.

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