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Updated: Mar 28, 2026

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
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神经炎症性TNFα通过星细胞信号破坏记忆

Samia Habbas1, Mirko Santello1, Denise Becker1

  • 1Department of Fundamental Neurosciences, University of Lausanne, Rue du Bugnon 9, 1005 Lausanne, Switzerland.

Cell
|December 22, 2015
PubMed
概括

在中枢神经系统炎症期间瘤死因α (TNFα) 的增加会损害认知功能. 这项研究显示TNFα激活天体细胞TNFR1,改变多发性硬化症模型中的海马突触和学习.

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