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Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization
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哺乳动物精子成熟和受精过程中的tRNA片段的生物发生和功能

Upasna Sharma1, Colin C Conine1, Jeremy M Shea1

  • 1Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Science (New York, N.Y.)
|January 2, 2016
PubMed
概括

父亲的饮食通过精子小RNA影响后代的新陈代谢. 饮食中的蛋白质限制会改变精子小RNA水平,包括转移RNA片段,这些片段会调节早期胚胎中的基因表达.

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