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结构洞察四重复-双重复3'接口形成的Telomeric重复:一个潜在的分子目标

Irene Russo Krauss1, Sneha Ramaswamy2, Stephen Neidle2

  • 1Department of Chemical Sciences, University of Naples Federico II , I-80126 Napoli, Italy.

Journal of the American Chemical Society
|January 6, 2016
PubMed
概括

研究人员研究了G四重复和人类端粒DNA之间的3'接口. 结构分析揭示了TAT三合体平台,为选择性小分子结合提供了潜在的目标.

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