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基于塑选择性蛋白酶体抑制剂的结构和功能设计

Hao Li1,2, Anthony J O'Donoghue3, Wouter A van der Linden1

  • 1Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature
|February 12, 2016
PubMed
概括

研究人员开发了选择性蛋白酶抑制剂来治疗疟疾. 这些化合物向Plasmodium蛋白酶体,对抗药物耐药的寄生虫具有最小的宿主毒性,提供了一个有前途的新抗疟疾策略.

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