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Small-Scale Plasma Membrane Preparation for the Analysis of Candida albicans Cdr1-mGFPHis
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通过破坏激活剂-调解剂相互作用来抑制真菌的多药性

Joy L Nishikawa1,2, Andras Boeszoermenyi3, Luis A Vale-Silva4

  • 1Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts 02129, USA.

Nature
|February 18, 2016
PubMed
概括

研究人员开发了一种小分子抑制剂 (iKIX1),以中介体为向,以对抗耐药性真菌感染. 这种方法使抗真菌药物耐药的Candida glabrata重新敏感,为传染病提供了一种新的治疗策略.

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