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罗斯肉瘤病毒的晶体结构

Zhiqi Yin1,2,3, Ke Shi1,2,3, Surajit Banerjee4

  • 1Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Nature
|February 19, 2016
PubMed
概括

复原病毒整合酶对于病毒DNA整合至关重要,形成一个八度复合体. 这种结构揭示了罗斯肉瘤病毒整合酶如何结合病毒和向DNA,为HIV-1整合机制提供了洞察力.

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