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通过质谱测量对纳米大小的多金属进行测量和发现

Andrew J Surman1, Philip J Robbins1, Jakub Ujma2

  • 1WestCHEM, School of Chemistry, University of Glasgow , Glasgow G12 8QQ, Scotland, United Kingdom.

Journal of the American Chemical Society
|February 25, 2016
PubMed
概括

聚氧金属酸盐 (POM) 现在作为离子移动性质谱 (IM-MS) 的可靠校准剂,使大纳米离子的特征和新分子结构的发现成为可能.

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Changes in polymorphic forms can significantly influence the bioavailability of poorly soluble drugs. Although the FDA defines pharmaceutical equivalence based on having the same active ingredient, dosage form, and route of administration, it does not automatically disqualify products with different polymorphic forms. This means two products with different polymorphs can still be deemed pharmaceutically equivalent. However, polymorphic differences can affect properties like wettability,...