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Updated: Mar 24, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

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菌酸合成酶是减少多基酸合成酶结构的例子

Dominik A Herbst1, Roman P Jakob1, Franziska Zähringer1

  • 1Department Biozentrum, University of Basel, Klingelbergstrasse 50/70, 4056 Basel, Switzerland.

Nature
|March 16, 2016
PubMed
概括

我们揭示了真菌菌中的一个关键酶的结构, 这一发现解释了多基合成酶 (PKS) 如何在重新设计中产生各种产品和辅助剂.

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The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli10:41

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