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Updated: Mar 23, 2026

Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery
08:21

Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery

Published on: June 28, 2019

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β-阿雷斯生物传感器显示了一个快速的,受体依赖的激活/失活周期

Susanne Nuber1,2, Ulrike Zabel1,2, Kristina Lorenz1,3

  • 1Institute of Pharmacology and Toxicology, University of Würzburg, Versbacher Str. 9, 97078 Würzburg, Germany.

Nature
|March 24, 2016
PubMed
概括

通过与激活受体结合来调节G蛋白合受体 (GPCR). 这项研究揭示了β-arrestins的受体特异性构造变化,表明受体解离后的快速激活周期和持续的信号潜力.

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Real-time Imaging of Leukotriene B4 Mediated Cell Migration and BLT1 Interactions with β-arrestin13:45

Real-time Imaging of Leukotriene B4 Mediated Cell Migration and BLT1 Interactions with β-arrestin

Published on: December 23, 2010

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