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Updated: May 7, 2026

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
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使用原生质谱法确定膜蛋白-脂质结合热力学

Xiao Cong1, Yang Liu1, Wen Liu1

  • 1Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Texas A&M Health Science Center , Houston, Texas 77030, United States.

Journal of the American Chemical Society
|March 26, 2016
PubMed
概括

我们开发了一种使用原生质谱法 (MS) 测量单个蛋白质脂质相互作用的热力学方法. 这种技术可以揭示不同的脂质的结合特征,并识别膜蛋白的关键结合点.

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相关概念视频

Mass Spectrometry: Overview01:19

Mass Spectrometry: Overview

Mass spectrometry is an analytical technique used to determine the molecular mass and molecular formula of a compound. The basic principle of mass spectrometry is to generate ions from the analyte molecule and measure these ion abundances against their molecular mass. One common type of ionization, known as electron ionization or EI, bombards the analyte molecules in the gas phase with high-energy electron beams. The electron beams displace an electron from the molecule and leave behind a...