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通过促进与IL-2灭树突细胞的相互作用,EBI2增加了Tfh细胞命运

Jianhua Li1,2,3, Erick Lu1,2, Tangsheng Yi1,2

  • 1Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California 94143, USA.

Nature
|May 6, 2016
PubMed
概括

G蛋白结合受体EBI2引导T毛囊辅助细胞 (Tfh) 到特定位置,而树突细胞则使用CD25控制IL-2并促进Tfh细胞分化以获得强大的免疫反应.

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