体质指数变化与丹麦死亡率最低,1976-2013年
Shoaib Afzal1, Anne Tybjærg-Hansen1, Gorm B Jensen2
1Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark2Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark3Section for Molecular Gen.
JAMA
|May 11, 2016
概括
在过去的30年中,与死亡风险最低的体质指数 (BMI) 增加了. 这种转变表明,随着时间的推移,人口健康和BMI与死亡率之间的关系发生了变化.
科学领域:
- 流行病学
- 公共卫生
- 心血管研究
背景情况:
- 身体质量指数 (BMI) 与死亡率之间的U形关联已得到充分证实.
- 全球平均体重指数上升,而心血管危险因素可能在肥胖人口中下降.
- 这些趋势表明,与所有原因死亡率最低的BMI可能会发生变化.
研究的目的:
- 调查与所有原因死亡率最低的体重指数 (BMI) 在30年内是否发生变化.
- 分析一般人群中BMI和死亡率的趋势.
主要方法:
- 对三组丹麦普通人口 (1976-1978,1991-1994,2003-2013) 进行长期跟踪的分析.
- 体重指数 (BMI) 建模使用分线和WHO类别;计算为体重 (kg) /身高 (m) ^2.
- 主要结果:全因死亡率;次要结果:因特定原因死亡率.
主要成果:
- 与所有原因死亡率最低的BMI从1976-1978年队列增加到2003-2013年队列的3.3个单位.
- 观察到BMI与全因,心血管和其他死亡率 (不包括癌症) 之间的U型关联.
- 与BMI为18. 5-24. 9的个体相比,所有原因的死亡风险比率在研究期间显著下降.
结论:
- 在1976年至2013年期间,与所有原因死亡率最低的身体质量指数 (BMI) 显著增加.
- 这种观察到的转变需要进一步的研究,以阐明潜在的原因和临床影响.
- 了解这些不断变化的BMI与死亡率的关系对于公共卫生战略和临床指南至关重要.
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