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癌细胞系面板的可复制药基因组分析

Peter M Haverty1, Eva Lin2, Jenille Tan2

  • 1Department of Bioinformatics and Computational Biology, Genentech Inc., 1 DNA Way, South San Francisco, California 94080, USA.

Nature
|May 20, 2016
PubMed
概括

癌细胞查中的可复制性至关重要. 本研究表明可实现的一致性,并概述了基因组和药物反应研究中的实验室和分析的最佳实践.

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
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