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相关概念视频

Hindsight Biases01:12

Hindsight Biases

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Hindsight bias leads you to believe that the event you just experienced was predictable, even though it really wasn’t. In other words, you knew all along that things would turn out the way they did. Can you relate this to the phrase "Hindsight is 20/20" now? 
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Cognitive Dissonance01:38

Cognitive Dissonance

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Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
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Classification of Illness01:17

Classification of Illness

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The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
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Self-Presentation: Self-Monitoring and Self-Handicapping02:05

Self-Presentation: Self-Monitoring and Self-Handicapping

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People can go to great lengths to protect their self-image and present themselves in ways that they want others to see them. Sociologist Erving Goffman presented the idea that a person is like an actor on a stage. Calling his theory dramaturgy, Goffman believed that we use “impression management” to present ourselves to others as we hope to be perceived. Each situation is a new scene, and individuals perform different roles depending on who is present (Goffman, 1959). Think about...
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Growth versus Fixed Mindset01:24

Growth versus Fixed Mindset

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Carol Dweck introduced the term mindset to describe individuals' beliefs about their intellectual and personal capabilities. These beliefs significantly influence psychological processes such as motivation, goal-setting, and perseverance, ultimately shaping academic and life outcomes. Individuals generally possess one of two mindsets- a fixed or a growth mindset—each promoting different responses to success, failure, and challenge.Fixed vs. Growth MindsetA fixed mindset assumes that one's...
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Retrieval01:12

Retrieval

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Retrieval is the process of getting information out of memory storage and back into conscious awareness. This ability is essential for daily tasks like brushing hair and teeth, driving to work, and performing job duties. Retrieval occurs in three ways: recall, recognition, and relearning.
Recall involves accessing information without cues, such as during an essay test, where individuals must retrieve facts and concepts from memory unaided. Another example is remembering the name of a colleague...
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相关实验视频

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Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
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一位正在康复的学术家的教训

Michael D Ehlers1

  • 1Biogen, 225 Binney Street, Cambridge, MA 02142, USA.

Cell
|May 21, 2016
PubMed
概括

桥梁基础生物学和治疗涉及学术和行业的合作. 这项工作澄清了两部门关于有效药物发现的科学实践的常见误解.

科学领域:

  • 生物医学研究
  • 药物发现和开发
  • 翻译科学

背景情况:

  • 将基本生物学发现转化为临床疗法需要综合科学努力.
  • 成功的药物开发计划需要跨学科和工业环境的合作.
  • 有效的翻译将实验室研究与临床验证联系起来.

研究的目的:

  • 描述学术与工业环境中科学运作的普遍观念和误解.
  • 提供一个更清晰的理解如何在不同领域进行药物发现.
  • 为加强学术界和工业界之间的合作制定战略.

主要方法:

  • 科学实践的概念分析.
  • 对学术研究中的运作模式进行审查.
  • 检查工业药物开发中的方法.

主要成果:

  • 确定学术界和工业界科学方法的具体差异和相似之处.
  • 突出了可能阻碍翻译研究的常见误解.
  • 强调基础科学与应用发展之间的关键相互作用.

结论:

  • 准确了解学术和工业科学文化对于成功的治疗翻译至关重要.

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  • 解决误解可以促进更有效的合作.
  • 综合方法是推动药物发现从临床到临床的关键.