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对尼曼-皮克C1 (NPC1) 介导的胆固醇转移和埃博拉感染的结构洞察

Xin Gong1, Hongwu Qian1, Xinhui Zhou1

  • 1State Key Laboratory of Membrane Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China; Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences and School of Medicine, Tsinghua University, Beijing 100084, China.

Cell
|May 31, 2016
PubMed
概括

对尼曼·皮克病C型 (NPC) 蛋白质NPC1的结构洞察力揭示了其在胆固醇运输和埃博拉病毒 (EBOV) 进入中的双重作用. 这项研究阐明了NPC1

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