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相关概念视频

The Thyroid Gland01:23

The Thyroid Gland

8.5K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
8.5K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.8K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.8K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

6.4K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
6.4K
Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
55.5K
Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Cancer Therapies02:49

Cancer Therapies

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相关实验视频

Updated: Mar 20, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

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甲状腺癌

Maria E Cabanillas1, David G McFadden2, Cosimo Durante3

  • 1Department of Endocrine Neoplasia and Hormonal Disorders, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Lancet (London, England)
|June 1, 2016
PubMed
概括
此摘要是机器生成的。

甲状腺癌的发病率正在全球上升. 虽然差异化甲状腺癌通常可以用标准方法治疗,但罕见的甲状腺癌需要专门的护理和针对性治疗.

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Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Spontaneous Murine Model of Anaplastic Thyroid Cancer

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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

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相关实验视频

Last Updated: Mar 20, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

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Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

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科学领域:

  • 癌症学
  • 内分泌学

背景情况:

  • 甲状腺癌是全球严重且日益严重的疾病.
  • 分化甲状腺癌 (DTC) 是最常见的亚型,标准治疗通常有效.
  • 罕见的亚型,包括骨髓性甲状腺癌 (MTC) 和形甲状腺癌 (ATC),存在独特的挑战.

研究的目的:

  • 总结目前的甲状腺癌发病率和治疗情况.
  • 突出不同类型甲状腺癌的不同治疗策略.
  • 讨论针对性治疗在晚期或晚期甲状腺癌中的作用.

主要方法:

  • 对甲状腺癌发病率的流行病学数据的审查.
  • 对差异化甲状腺癌标准治疗方案的分析.
  • 对甲状腺骨髓癌和形甲状腺癌的专用方法的讨论.
  • 对已批准的甲状腺癌向治疗的评估.

主要成果:

  • 甲状腺癌的发病率在全球上升,
  • 对于大多数患者来说,标准的DTC治疗 (手术加放射性或观察) 是有效的.
  • 针对DTC和MTC的向治疗可以延长无进展的存活时间,但不能治愈,只适用于进展或有症状的病例.

结论:

  • 甲状腺癌的有效治疗取决于准确的亚型和适当的治疗选择.
  • 专门的专业知识对于治疗罕见和侵袭性甲状腺癌亚型至关重要.
  • 虽然有针对性的疗法对晚期疾病有好处,但它们强调了对治疗方法的持续研究的需要.