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Updated: Jan 8, 2026

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice
09:35

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice

Published on: January 20, 2015

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直接识别数以百计的表达式调节变体,使用多重复的报告测试

Ryan Tewhey1, Dylan Kotliar1, Daniel S Park2

  • 1Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA; Broad Institute, Cambridge, MA 02142, USA.

Cell
|June 4, 2016
PubMed
概括

这项研究采用了大规模并行报告测试 (MPRA) 来识别直接影响基因表达的遗传变异. 该方法成功地确定了842种变异,包括与疾病相关的变异,为非编码DNA提供了新的洞察力.

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