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Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
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系统性RNA输送到树突细胞利用抗病毒防御进行癌症免疫治疗

Lena M Kranz1,2, Mustafa Diken1,3, Heinrich Haas3

  • 1TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.

Nature
|June 10, 2016
PubMed
概括

静脉注射的RNA- lipoplex (RNA- LPX) 在体内有效向树突细胞 (DCs) 进行强烈的T细胞反应. 这种新型疫苗平台诱导了强大的适应性和先天性免疫力,

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