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Experimental Analysis of Apoptotic Thymocyte Engulfment by Macrophages
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细胞微粒中染色体的消化防止自身免疫

Vanja Sisirak1, Benjamin Sally2, Vivette D'Agati3

  • 1Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.

Cell
|June 14, 2016
PubMed
概括

在全身性红斑狼 (SLE) 中,DNASE1L3功能的丧失使得与微粒相关的染色体能够触发自身抗体. 恢复DNASE1L3可能为SLE患者提供治疗策略.

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