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Updated: May 8, 2026

Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery
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Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery

Published on: June 23, 2011

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具有精致的HIV-1中和活性的两种特异性抗体

Yaoxing Huang1, Jian Yu1, Anastasia Lanzi1

  • 1Aaron Diamond AIDS Research Center, The Rockefeller University, 455 First Avenue, New York, NY 10016, USA.

Cell
|June 18, 2016
PubMed
概括

设计的双特异性抗体提供强大的HIV-1中和作用. 这些新型药物显示出被动免疫的潜力, 潜在地预防和治疗HIV-1感染.

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Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model

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Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells10:19

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells

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相关概念视频

Enzyme-Linked Immunosorbent Assay01:33

Enzyme-Linked Immunosorbent Assay

In 1971, Peter Perlman and Eva Engvall developed an Enzyme-linked immunosorbent assay (ELISA or EIA). ELISA differs from western blot in that the assays are conducted in microtiter plates or in vivo rather than on an absorbent membrane.
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen.  Enzyme-substrate reaction allows the antigen to be visualized or quantified.