植物性疗法和更年期症状的使用:系统审查和元分析
Oscar H Franco1, Rajiv Chowdhury2, Jenna Troup1
1Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
JAMA
|June 22, 2016
概括
植物性雌激素补充剂适度减少更年期妇女的发热和阴道干燥,但不能减少夜间出汗. 由于研究质量问题,需要进行更多的研究.
科学领域:
- 绝经研究
- 植物疗法
- 女性健康
背景情况:
- 许多女性使用补充疗法来治疗更年期症状.
- 植物性疗法是治疗这些症状的常见选择.
研究的目的:
- 评估植物性疗法对更年期症状的有效性.
- 特别是检查热,夜间出汗和阴道干燥.
主要方法:
- 随机临床试验的系统审查和元分析.
- 搜索了Ovid MEDLINE,EMBASE和Cochrane中央的数据库.
- 包括62项涉及6653名女性的研究.
主要成果:
- 植物性雌激素可以缓解炎热和阴道干燥.
- 没有观察到对夜间出汗的显著影响.
- 一些草药有助于缓解血管运动症状.
结论:
- 植物雌激素补充剂可以缓解发热和阴道干燥.
- 证据质量低于最佳,具有显著的异质性.
- 需要进一步的高质量研究来证实这些发现.
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