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相关概念视频

Urinary Bladder01:23

Urinary Bladder

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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
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Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

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Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
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Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
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Nursing Assessment of the Genitourinary System II: Inspection and Palpation01:26

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

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The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
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Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
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Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

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Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
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An Orthotopic Bladder Cancer Model for Gene Delivery Studies
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膀癌

Ashish M Kamat1, Noah M Hahn2, Jason A Efstathiou3

  • 1Department of Urology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Lancet (London, England)
|June 28, 2016
PubMed
概括
此摘要是机器生成的。

早期诊断和量身定制的治疗对于治疗膀癌至关重要. 治疗策略从非肌肉侵入性瘤的静脉注射疗法到肌肉侵入性疾病的激进囊切除术或膀节省选择,在晚期出现的免疫疗法.

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科学领域:

  • 尿道病学
  • 癌症学
  • 医学研究

背景情况:

  • 如果没有有效的治疗,膀癌会导致严重的发病率和死亡率.
  • 血是一个关键的症状,强调需要及时诊断和个性化护理.
  • 最佳的治疗和随访对于成功的患者结果至关重要.

研究的目的:

  • 概述目前的膀癌诊断和治疗模式.
  • 根据癌症阶段的个性化治疗策略的重要性.
  • 讨论新兴的治疗方法和最近的遗传发现的影响.

主要方法:

  • 对非肌肉侵入性膀癌 (NMIBC) 已建立的治疗方案的审查.
  • 对肌肉侵入性膀癌 (MIBC) 的多模式治疗方案的分析.
  • 对晚期膀癌的全身化疗和免疫疗法的评估.
  • 考虑节省膀的三种治疗方案.

主要成果:

  • 完整的瘤切除,然后进行静脉免疫疗法 (BCG疫苗) 或化疗是NMIBC的标准.
  • 用新辅助化疗进行的急切囊切除术为MIBC提供了最好的治愈潜力.
  • 对于某些MIBC患者来说,节省膀的三种治疗是一种可行的选择.
  • 系统化疗是晚期疾病的首要治疗方法,免疫疗法是救援选择.

结论:

  • 个性化治疗方法,从腹腔内疗法到激进手术和化疗,对于膀癌的治疗至关重要.
  • 对基因亚型的新兴研究可能进一步完善治疗选择并改善患者的反应.
  • 根据疾病阶段和患者因素进行持续的跟踪和治疗调整至关重要.