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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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Published on: March 2, 2014

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一种核心病毒蛋白与宿主核细胞结合,隔离免疫危险信号

Daphne C Avgousti, Christin Herrmann, Katarzyna Kulej

    Nature
    |July 1, 2016
    PubMed
    概括

    腺病毒蛋白VII通过结合核细胞改变宿主染色体结构,影响抗病毒反应. 这种病毒蛋白封存高流动性组蛋白B1 (HMGB1), 防止其释放并抑制免疫信号.

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