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Updated: Mar 18, 2026

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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Published on: September 18, 2014

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赫克索金酶是一种天生的免疫受体,用于检测细菌糖

Andrea J Wolf1, Christopher N Reyes2, Wenbin Liang3

  • 1F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Cell
|July 5, 2016
PubMed
概括

格拉姆阳性细菌通过N-乙葡萄糖胺激活NLRP3炎症酶,由代谢酶hexokinase检测到. 这一发现揭示了一种代谢酶作为模式识别受体,影响免疫反应.

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