人类发育生物学的微生物视角
Mark R Charbonneau1,2, Laura V Blanton1,2, Daniel B DiGiulio3,4
1Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Nature
|July 8, 2016
概括
人类发展包括微生物群落, 提供定义健康生长和预防疾病的新途径. 建立一个
科学领域:
- 微生物学
- 人类发展
- 微生物组研究
背景情况:
- 人类的发展传统上集中在细胞和器官的生长上.
- 人类相关的微生物群落在发展中起着至关重要的,但往往被忽视的作用.
- 了解微生物组是人类成长的关键.
研究的目的:
- 突出微生物群落在人类发展中的重要性.
- 通过微生物镜头提出疾病预防和治疗的新战略.
- 倡导建立新的研究基础设施来研究微生物的发展.
主要方法:
- 这项研究是一个概念和基于提案的审查.
- 它综合了关于人类微生物组和发展的现有知识.
- 它呼吁建立具体的研究倡议.
主要成果:
- 微生物视角精确了健康的产前和产后生长的定义.
- 整合微生物组研究可以导致创新的疾病预防和治疗策略.
- 全球生活方式和疾病模式的变化需要新的研究方法.
结论:
- 人类微生物组是人类发展的重要组成部分.
- 建立"人类微生物观测站"对于研究微生物社区发展至关重要.
- 研究应集中在不同的出生群体,以了解微生物发育的变化.
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