组织工程软机器人射线的光学指导
Sung-Jin Park1, Mattia Gazzola2, Kyung Soo Park3
1Disease Biophysics Group, Wyss Institute for Biologically Inspired Engineering, John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
Science (New York, N.Y.)
|July 9, 2016
概括
研究人员使用老鼠心脏细胞和黄金骨设计了一种生物混合光线. 这种人造鱼游泳并遵循灯光线索,
科学领域:
- 生物混合系统
- 组织工程
- 机器人技术
- 视觉遗传学
背景情况:
- 类鱼 (如鱼,滑板鱼) 具有简单但有效的水中运动形态.
- 开发生物混合系统为创造自主,生物启发的机器提供了一种新的方法.
- 控制生物混合系统的外部刺激,如光,对于实际应用至关重要.
研究的目的:
- 为了设计一个1/10的尺度, 组织工程射线能够波浪游泳.
- 通过光遗传学来实现生物混合系统的光学指导和控制.
- 复制鱼中观察到的基本曲模式.
主要方法:
- 用微型制造的黄金骨架将老鼠心肌细胞分离到一个弹性体上.
- 使用光遗传学来激活肌肉和控制翅膀的运动.
- 使用蛇形形状的肌肉电路进行协调的波动推进.
主要成果:
- 成功创造了一种模仿鱼形态和游泳模式的生物混合射线.
- 证明光学导向,使光线能够遵循光线线索.
- 通过调节光频和选择性激活来实现可控速度和方向,允许通过障碍路径进行导航.
结论:
- 这项研究提出了一个可行的生物混合系统,用于制造自动驾驶,光导水上机器人.
- 光遗传学为工程生物的复杂动作提供了精确的肌肉激活控制.
- 这项研究为开发先进的传感和运动生物杂交机器铺平了道路.
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