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评估寨卡病毒的全球威胁

Justin Lessler¹, Lelia H Chaisson², Lauren M Kucirka³

¹Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. justin@jhu.edu.

Science (New York, N.Y.)

|July 16, 2016

概括

曾经不为人知的寨卡病毒 (ZIKV) 感染因与小头症的联系而引起全球关注. 这次审查考察了ZIKV

科学领域:

流行病学
病毒学
公共卫生

背景情况:

寨卡病毒 (ZIKV) 首次在1947年被发现,但仍然是一个鲜为人知的热带疾病.
2015年巴西小头病例的显著增加引起了全球的关注.
对于影响全球ZIKV感染威胁及其并发症的因素的了解有限.

研究的目的:

审查目前关于ZIKV感染的流行病学和自然史的知识.
评估ZIKV对公众健康的影响.
确定有关ZIKV的关键知识缺口.

主要方法:

对现有寨卡病毒研究的文献综述.
与ZIKV爆发相关的流行病学数据的分析.
综合有关ZIKV感染自然史和临床表现的信息.

主要成果:

该审查巩固了关于ZIKV流行病学和自然史的信息.
讨论公共卫生影响和当前知识的经验基础.
需要进一步研究的重点领域.

结论:

对ZIKV的流行病学和自然史的全面了解至关重要.
解决知识差距对于减轻ZIKV的全球威胁至关重要.
需要进一步的研究,以充分了解和管理ZIKV感染及其后果.

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