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Updated: Mar 17, 2026

ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast
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在3.5 Å分辨率下激活酵母结合体的结构

Chuangye Yan1, Ruixue Wan1, Rui Bai1

  • 1Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Science (New York, N.Y.)
|July 23, 2016
PubMed
概括

这项研究揭示了激活结合体 (Bact复合体) 的原子结构,详细说明了U2,U5和U6小核RNA如何与前传递 RNA相互作用以启动结合. 这为了解mRNA前拼接机制提供了一个分子框架.

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