行为激活与抑郁症认知行为治疗 (COBRA) 的成本和结果:一个随机对照的非劣势试验
David A Richards1, David Ekers2, Dean McMillan3
1Medical School, University of Exeter, Exeter, UK.
Lancet (London, England)
|July 28, 2016
概括
行为激活与认知行为治疗同样有效. 这种简单的疗法可以由不太专业的心理健康工作者提供,
科学领域:
- 精神病学
- 临床心理学
- 健康经济学
背景情况:
- 抑郁症是一种普遍且代价高昂的精神疾病.
- 认知行为治疗 (CBT) 是有效的, 但复杂和昂贵.
- 行为激活提供了一个更简单,更具成本效益的替代方案.
研究的目的:
- 对于患有抑郁症的成年人来说,比较BA与CBT的临床疗效和成本效益.
- 确定BA在治疗抑郁症症状方面是否与CBT相比.
主要方法:
- 一个随机的,受控的,非劣等性试验, 涉及被诊断患有严重抑郁症的成年人.
- 参与者被随机分配到接受BA或CBT.
- 在12个月后使用患者健康问卷9 (PHQ-9) 评估抑郁症症状.
主要成果:
- 行为激活 (BA) 发现与认知行为治疗 (CBT) 不相差.
- 在BA和CBT组中,12个月的PHQ-9平均得分相似 (在修改后的治疗意向群体中为8. 4).
- 两组治疗者之间没有发现严重不良事件的显著差异.
结论:
- 行为激活 (BA) 是治疗抑郁症的临床有效和非劣质替代方案.
- 可以由初级精神卫生工作者提供,
- 这表明,在不需要高专业和昂贵的专业人士的情况下, 可以提供有效的心理治疗.
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