急性心肌梗塞
Grant W Reed1, Jeffrey E Rossi1, Christopher P Cannon2
1Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA.
Lancet (London, England)
|August 10, 2016
概括
通过同样对待ST升高和非ST升高的MI来简化急性心肌梗塞 (AMI) 的治疗. 在反注血,抗血小板治疗和二次预防方面取得的进展改善了这一主要死亡原因的结果.
科学领域:
- 心脏病学
- 内部医学
- 公共卫生
背景情况:
- 急性心肌梗塞 (AMI) 是全球发病率和死亡率的主要原因.
- 尽管有所改善,但AMI仍然是一个全球性的健康挑战.
- 传统的分类为ST-elevationMI和非ST-elevationMI可以简化管理.
研究的目的:
- 审查AMI的病理生理学,流行病学和现代管理.
- 突出 AMI 的再输血策略和药物治疗的最新进展.
- 强调一个统一的AMI管理方法.
主要方法:
- 对AMI病理生理学和流行病学当前文献的综述.
- 分析风险分层和侵入性策略的趋势.
- 对抗血小板药物,抗凝固药物和他类药物治疗的进展进行评估.
- 讨论当代的再注血技术,包括穿皮冠状动脉干预和纤维解析.
主要成果:
- 在过去十年中,AMI预后取得了显著进展.
- 增加了侵入性策略的使用和快速的再血管化.
- 增加抗血小板和抗凝固药物的疗效.
- 更多地采用像他类药物这样的二次预防措施.
结论:
- 简化和统一的AMI管理方法是可行的和有益的.
- 为了改善AMI的结果,对再输血和药物治疗的持续进展至关重要.
- 有效的二次预防策略对于减少长期发病率和死亡率至关重要.
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