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Updated: Mar 16, 2026

Functionalization of Atomic Force Microscope Cantilevers with Single-T Cells or Single-Particle for Immunological Single-Cell Force Spectroscopy
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Functionalization of Atomic Force Microscope Cantilevers with Single-T Cells or Single-Particle for Immunological Single-Cell Force Spectroscopy

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使用原子力显微镜对单细胞中的微RNA进行可视化和量化

Hyunseo Koo1, Ikbum Park1, Yoonhee Lee1

  • 1Department of Chemistry, ‡Division of Integrative Biosciences and Biotechnology, and §Department of Life Sciences, Pohang University of Science and Technology , 77 Cheongam-Ro, Nam-Gu, Pohang 37673, Korea.

Journal of the American Chemical Society
|August 17, 2016
PubMed
概括

我们开发了一种敏感的原子力显微镜 (AFM) 方法来量化单细胞中的微RNA (miRNA). 这种技术精确地绘制了miRNA分布和表达水平, 进步了我们对细胞过程和癌症等疾病的理解.

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Measuring the Mechanical Properties of Living Cells Using Atomic Force Microscopy

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Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

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相关概念视频

Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
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