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孕产妇免疫激活:对神经精神疾病的影响

Myka L Estes1, A Kimberley McAllister2

  • 1Center for Neuroscience, University of California Davis, One Shields Avenue, Davis, CA 95618, USA.

Science (New York, N.Y.)
|August 20, 2016
PubMed
概括

怀孕期间母亲免疫激活会导致子女终身脑部变化和行为问题,增加自闭症和精神分裂症的风险. 需要进一步的研究来了解这些神经免疫性疾病并开发治疗方法.

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Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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