,

Marco Sciacovelli1, Emanuel Gonçalves2, Timothy Isaac Johnson1

  • 1Medical Research Council Cancer Unit, University of Cambridge, Cambridge CB2 0XZ, UK.

Nature
|September 1, 2016
PubMed
概括

烟酸酶的损失导致烟酸的积累,促进了侵袭性癌. 通过抑制表观遗传调节剂,驱动上皮细胞转化为介质细胞,导致转移和不良结果.

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