在成年人中查潜伏性结核病感染:美国预防服务工作组建议声明
, Kirsten Bibbins-Domingo1, David C Grossman2
1University of California, San Francisco.
JAMA
|September 7, 2016
概括
对于高风险的个人,建议进行潜伏结核感染 (LTBI) 查. 在预防活跃结核病方面,LTBI的治疗提供了适度的益处,并带来了最小的危害.
科学领域:
- 公共卫生
- 预防医学
- 传染病流行病学
背景情况:
- 在美国,结核病是可预防的重大疾病.
- 识别和治疗潜伏性结核感染 (LTBI) 是减少结核传播,疾病和死亡的关键.
- 防止从长期结核病发展为活跃结核病是公共卫生的主要目标.
研究的目的:
- 提供美国预防服务工作组 (USPSTF) 关于LTBI查的最新建议.
- 提供有关LTBI查的当前指南的初级保健实践.
主要方法:
- 在初级保健中对无症状成年人进行LTBI查的系统审查.
- 包括最早可用的数据库记录中的证据.
主要成果:
- 有准确的LTBI查测试.
- 对LTBI的治疗在预防活跃疾病进展方面提供了适度的益处.
- 与LTBI查和治疗相关的危害被认为是小的.
结论:
- USPSTF建议在被确定为风险增加的人群中进行LTBI查.
- 该建议被指定为"B"建议,表明中等净收益的高度确定性.
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