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Updated: Mar 15, 2026

Quick Fluorescent In Situ Hybridization Protocol for Xist RNA Combined with Immunofluorescence of Histone Modification in X-chromosome Inactivation
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m(6) 一种RNA甲基化促进XIST介导的转录抑制

Deepak P Patil1, Chun-Kan Chen2, Brian F Pickering1

  • 1Department of Pharmacology, Weill-Cornell Medical College, Cornell University, New York, New York 10065, USA.

Nature
|September 8, 2016
PubMed
概括

长非编码RNAXIST被RBM15/RBM15B甲基化,影响基因沉默. YTHDC1识别了这些标记,证明在转录抑制中对XIST功能至关重要.

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