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Updated: Mar 15, 2026

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions
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综合方法确定Robo1的肝硫酸配体需求

Chengli Zong, Rongrong Huang, Eduard Condac

  • 1Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, and Bijvoet Center for Biomolecular Research, Utrecht University , Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.

Journal of the American Chemical Society
|September 10, 2016
PubMed
概括

研究人员开发了一种新的方法来确定人体圆周受体1 (Robo1) 等蛋白质的肝酸硫酸 (HS) 结合要求. 这种方法揭示了对HS连接体相互作用至关重要的特定结构特征,影响细胞迁移.

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