胸外麻醉可降低右心室缩功能,同时保持心室-肺合
Jeroen Wink1, Rob B P de Wilde2, Patrick F Wouters2
1From the Department of Anesthesiology (J.W., E.L.A.v.D., B.T.V., L.P.H.J.A.), Department of Intensive Care (R.B.P.d.W.), Department of Cardiothoracic Surgery (M.I.M.V.), and Department of Cardiology (P.S.), Leiden University Medical Center, The Netherlands; and the Department of Anesthesia, University Hospitals Ghent, Belgium (P.F.W.). j.wink@lumc.nl.
胸外麻醉会损害右心室收缩能力,但保留了对增加后负荷的反应. 随着后负荷的增加,心室-肺合会减少,而不会受到这种麻醉的影响.
科学领域:
- 心脏病学
- 麻醉学
- 肺部医学
背景情况:
- 胸外麻醉 (TEA) 可能影响右心室 (RV) 功能及其与后负荷的相互作用.
- 对于接受胸部手术的患者来说,了解这些影响至关重要.
研究的目的:
- 研究TEA对RV功能的影响.
- 评估TEA对RV功能和RV后载的合的影响.
主要方法:
- 研究了10名接受肺切除的患者.
- 在TEA之前和之后使用压导导管测量了RV功能和对肺动脉紧的反应 (增加后负荷).
主要成果:
- TEA显著降低了VR的收缩性和缩功能.
- 有效的动脉弹性也下降,保持了心室-肺合.
- 肺动脉紧增加后负荷,增强RV收缩性但降低合;这些反应在TEA前和后相似.
结论:
- TEA 损害了 RV 的收缩性,但并没有取消 RV 对增加后负载的无otropic 反应.
- 通过增加后负载减少了心室-肺合,独立于TEA诱导.
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