双 [7] 异烯的合成,结构和手术性质
Xiao-Ye Wang1, Xin-Chang Wang2, Akimitsu Narita1
1Max Planck Institute for Polymer Research , Ackermannweg 10, 55128 Mainz, Germany.
Journal of the American Chemical Society
|September 23, 2016
概括
研究人员合成了一种新型的双重, 它独特的扭曲结构提供了卓越的性稳定性和高的异构化障碍.
科学领域:
- 有机化学
- 超分子化学
- 材料科学
背景情况:
- 体是具有独特螺旋结构的体分子.
- 双螺旋体具有更高的结构复杂性和高级应用的潜力.
- 在复杂的有机分子中实现高性稳定性仍然是一个重大挑战.
研究的目的:
- 合成一种新型的大型双环,
- 研究合成分子的结构,电子和光学特性.
- 在双基系统中建立一个新的基准.
主要方法:
- 合成的双联脱甲基化-玻里化反应.
- 单晶X射线衍射用于结构阐明.
- 石化高性能液体染色学 (HPLC) 用于同位素分离.
- 异构化障碍分析的理论计算
主要成果:
- 成功合成11a,25a-dibora-11,12,25,26-tetraoxatetranaphtho [1,2-a:2',1'-f:1′′,2′′-j:2′′′,1′′′-o] 烯,一种双 [7] 乙烯.
- 通过X射线分析证明具有高度扭曲的结构.
- 测定了最高的理论异构化障碍 (45.1 kcal/mol),表明异常的性稳定性.
- 分离 (P,P) - 和 (M,M) - 异构体,并描述它们的独特光学特性,包括相反的圆形二重化.
结论:
- 合成的双环代表了迄今为止最大的六个环系统.
- 由于其独特的扭曲形状,该分子具有显著的结构刚性和高性稳定性.
- 这项工作为开发具有分子识别和酶选择性催化学的潜在应用的先进性材料提供了新的平台.
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