寨卡病毒:免疫力和疫苗开发
Theodore C Pierson1, Barney S Graham2
1Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Cell
|October 4, 2016
概括
寨卡病毒爆发需要快速开发疫苗以预防严重的神经发育缺陷. 有望的疫苗候选人为控制寨卡病毒传播和疾病提供了希望.
科学领域:
- 病毒学
- 免疫学
- 公共卫生
背景情况:
- 寨卡病毒在美洲和加勒比地区的出现构成了严重的公共卫生威胁.
- 在怀孕期间感染寨卡病毒会导致婴儿严重的神经发育缺陷.
研究的目的:
- 总结一下对寨卡病毒疫苗的迫切需要.
- 突出了解寨卡免疫力和疫苗开发的进展.
主要方法:
- 关于寨卡病毒免疫力的最新科学文献的审查.
- 对正在进行的寨卡疫苗候选人的分析.
主要成果:
- 在了解寨卡病毒免疫学方面取得了重大进展.
- 几种有前途的寨卡疫苗正在开发中.
结论:
- 对寨卡病毒的预防措施越来越可行.
- 持续的研究和开发对于全球卫生安全至关重要.
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