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Updated: Mar 13, 2026

Monitoring Protein Aggregation Kinetics In Vivo using Automated Inclusion Counting in Caenorhabditis elegans
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聚胺的自由能量景观重复

Mingchen Chen1, MinYeh Tsai1, Weihua Zheng1

  • 1Center for Theoretical Biological Physics, ‡Department of Bioengineering, and §Department of Chemistry, Rice University , Houston, Texas 77005, United States.

Journal of the American Chemical Society
|October 28, 2016
PubMed
概括

具有多重胺 (polyQ) 重复的蛋白质聚合物与神经退行性疾病有关. 这项研究揭示了多Q重复的长度如何影响蛋白质结构和聚合,影响疾病的严重程度.

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