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在心肌梗塞的早期阶段识别患有心脏骤停的患者:e-MUST研究 (Evaluation en Médecine d' Urgence des Stratégies Thérapeutiques des infarctus du myocarde)

Nicole Karam ¹, Sophie Bataille ², Eloi Marijon ²

¹From Sudden Death Expertise Center, Paris, France (N.K., E.M., M.T., C.S., J.-P.E., X.J.); Université Paris Descartes, Sorbonne Paris Cité, Paris, France (N.K., E.M., M.T., C.S., J.-P.E., X.J.); Cardiology Department, European Georges Pompidou Hospital-APHP, Paris, France (N.K., E.M., C.S., X.J.); Paris Cardiovascular Research Center, INSERM Unit 970, Paris, France (N.K., E.M., O.G., M.T., M.M., C.S., J.-P.E., X.J.); Regional Health Agency of Ile-de-France, Paris, France (S.B.); Emergency Department, Centre Hospitalier Régional d'Orléans, Orléans, France (O.G.); SAMU 74, Réanimation, Annecy, France (D.S.); Cardiology Department, Institut Cardiovasculaire Paris Sud, Massy, France (H.B.); Cardiology Department, Institut Mutualiste Montsouris, Paris, France (C.C.); Cardiology Department, Institut Cardiovasculaire Paris Sud, Quincy sous Sénart, France (P.G.); Cardiology Department, Bichat Hospital-APHP, Paris, France (J.-M.J.); SAMU 77, Melun Hospital, Melun, France (V.P.); SAMU 94, Mondor Hospital-APHP, Créteil, France (T.B.); SAMU 95, Pontoise Hospital, Pontoise, France (F.D.); SAMU 92, Garches Hospital-APHP, Garches, France (G.L.B.); SAMU 75, Necker Hospital-APHP, Paris, France (L.L.); SAMU 91, Sud Francilien Hospital, Corbeil-Essonnes, France (F.L.); Fire Brigade of Paris, Paris, France (H.L.); SAMU 93, Avicenne Hospital-APHP, Bobigny, France (F.L.); and SAMU 78, Versailles Hospital, Le Chesnay, France (Y.L.). nicole_karam@hotmail.com.
²From Sudden Death Expertise Center, Paris, France (N.K., E.M., M.T., C.S., J.-P.E., X.J.); Université Paris Descartes, Sorbonne Paris Cité, Paris, France (N.K., E.M., M.T., C.S., J.-P.E., X.J.); Cardiology Department, European Georges Pompidou Hospital-APHP, Paris, France (N.K., E.M., C.S., X.J.); Paris Cardiovascular Research Center, INSERM Unit 970, Paris, France (N.K., E.M., O.G., M.T., M.M., C.S., J.-P.E., X.J.); Regional Health Agency of Ile-de-France, Paris, France (S.B.); Emergency Department, Centre Hospitalier Régional d'Orléans, Orléans, France (O.G.); SAMU 74, Réanimation, Annecy, France (D.S.); Cardiology Department, Institut Cardiovasculaire Paris Sud, Massy, France (H.B.); Cardiology Department, Institut Mutualiste Montsouris, Paris, France (C.C.); Cardiology Department, Institut Cardiovasculaire Paris Sud, Quincy sous Sénart, France (P.G.); Cardiology Department, Bichat Hospital-APHP, Paris, France (J.-M.J.); SAMU 77, Melun Hospital, Melun, France (V.P.); SAMU 94, Mondor Hospital-APHP, Créteil, France (T.B.); SAMU 95, Pontoise Hospital, Pontoise, France (F.D.); SAMU 92, Garches Hospital-APHP, Garches, France (G.L.B.); SAMU 75, Necker Hospital-APHP, Paris, France (L.L.); SAMU 91, Sud Francilien Hospital, Corbeil-Essonnes, France (F.L.); Fire Brigade of Paris, Paris, France (H.L.); SAMU 93, Avicenne Hospital-APHP, Bobigny, France (F.L.); and SAMU 78, Versailles Hospital, Le Chesnay, France (Y.L.).

⁰From Sudden Death Expertise Center, Paris, France (N.K., E.M., M.T., C.S., J.-P.E., X.J.); Université Paris Descartes, Sorbonne Paris Cité, Paris, France (N.K., E.M., M.T., C.S., J.-P.E., X.J.); Cardiology Department, European Georges Pompidou Hospital-APHP, Paris, France (N.K., E.M., C.S., X.J.); Paris Cardiovascular Research Center, INSERM Unit 970, Paris, France (N.K., E.M., O.G., M.T., M.M., C.S., J.-P.E., X.J.); Regional Health Agency of Ile-de-France, Paris, France (S.B.); Emergency Department, Centre Hospitalier Régional d'Orléans, Orléans, France (O.G.); SAMU 74, Réanimation, Annecy, France (D.S.); Cardiology Department, Institut Cardiovasculaire Paris Sud, Massy, France (H.B.); Cardiology Department, Institut Mutualiste Montsouris, Paris, France (C.C.); Cardiology Department, Institut Cardiovasculaire Paris Sud, Quincy sous Sénart, France (P.G.); Cardiology Department, Bichat Hospital-APHP, Paris, France (J.-M.J.); SAMU 77, Melun Hospital, Melun, France (V.P.); SAMU 94, Mondor Hospital-APHP, Créteil, France (T.B.); SAMU 95, Pontoise Hospital, Pontoise, France (F.D.); SAMU 92, Garches Hospital-APHP, Garches, France (G.L.B.); SAMU 75, Necker Hospital-APHP, Paris, France (L.L.); SAMU 91, Sud Francilien Hospital, Corbeil-Essonnes, France (F.L.); Fire Brigade of Paris, Paris, France (H.L.); SAMU 93, Avicenne Hospital-APHP, Bobigny, France (F.L.); and SAMU 78, Versailles Hospital, Le Chesnay, France (Y.L.). nicole_karam@hotmail.com.

Circulation +

2016年十月30日

在PubMed上查看摘要

概括

一个新的评分识别ST段升高心肌梗塞 (STEMI) 患者在到达医院之前患有突发心脏骤停 (SCA) 的高风险. 这种工具有助于紧急医疗服务对经历SCA的STEMI患者进行快速分拣和干预.

科学领域

心脏病学
紧急医疗
公共卫生

背景情况

在ST段升高心肌梗塞 (STEMI) 的住院死亡率显著下降.
在STEMI患者中,急性心脏骤停 (SCA) 的医院前死亡率仍然很高.
识别高风险的STEMI患者的医院前SCA对于及时的实地干预至关重要.

研究的目的

在ST段升高心肌梗塞 (STEMI) 患者中确定医院前突然心脏骤停 (SCA) 的预测因素.
在STEMI患者中开发和验证医院前SCA的预测得分.
评估评分在优化紧急医疗服务 (EMS) 管理中的实用性.

主要方法

一项由EMS在巴黎大区管理的STEMI患者的前性,基于人口的研究 (2006-2010).
确定与医院前SCA风险相关的特征.
开发和内部/外部验证5个预测SCA风险评分.

主要成果

在8112名STEMI患者中,SCA发生在5. 6%的患者中.
主要预测SCA的因素包括年轻年龄,没有肥胖/糖尿病,呼吸短促,以及短暂的EMS前呼叫延迟.
SCA风险得分显示出显著的预测价值,较高得分的风险大幅增加 (例如,得分≥30的风险是18倍).

结论

一个简单的5预测得分可以确定STEMI早期的医院前SCA风险.
这一分数可以帮助EMS优化患者的发送和管理.
该评分有助于对STEMI患者进行风险分层,从而可能改善结果.

关键词:

动脉样硬化死亡,突然,心脏病心肌梗塞预后情况

在心肌梗塞的早期阶段识别患有心脏骤停的患者:e-MUST研究 (Evaluation en Médecine d' Urgence des Stratégies Thérapeutiques des infarctus du myocarde)

概括

科学领域

背景情况

研究的目的

主要方法

主要成果

结论

关键词:

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在心肌梗塞的早期阶段识别患有心脏骤停的患者:e-MUST研究 (Evaluation en Médecine d' Urgence des Stratégies Thérapeutiques des infarctus du myocarde)

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概括

科学领域

背景情况

研究的目的

主要方法

主要成果

结论

关键词:

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